Transdermal medication, on the other hand, is perfect for sports injuries since the drug can be placed right on the area where the injury occurs. Not only is it safer for the body, it is much more effective. One of the most effective drugs, doctors are now prescribing for topical treatment, is Ketoprofen, an NSAID, that has been used for internal care and is now available as a topical.
“A study performed by Alarcon, et al, comparing the topical penetration of various NSAIDS-non-steroidal anti-inflammatory drugs (ketoprofen, ketorlac, indomethacin, etc), found that Ketoprofen had the best permeating ability within its class. Other studies have found that topical formulations of ketoprofen demonstrate effectiveness for the treatment of well-localized soft-tissue injury and joint pain, as well as being effective in reducing muscle soreness after repetitive muscle contraction. These studies also demonstrate the maintenance of a low rate and extent of systemic absorption with no reported adverse events. Transdermal ketoprofen has a relatively fast onset of action, being able to suppress pain ratings by 51% in patients within an hour of application, when compared with placebo.” (Mazieres, B, Rouanet, S, Velicy, J; Topical Ketoprofen Patch (100 mg) for the treatment of Ankle Sprain, a randomized, double-blind, placebo-controlled study; American Journal of Sports Medicine, 2005, 33 (4) 515-524)
How would you use a topical pain medication like Ketoprofen instead of an oral medication?