Why Compounding?

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At A&R Pharmacy, we take pride in the quality assurance of our compounded medications which are regulated by the USP, U.S. Pharmacopeial Convention. Every compounding pharmacy must comply with the regulations set by the State Board of Pharmacy of the state in which the pharmacy is located. Each State Board of Pharmacy has the power to set and enforce regulations for compounding in its state, just as traditional pharmacies are regulated. The ingredients used by compounding pharmacies to make compounds come from FDA-registered and inspected facilities. We do take further steps to verify quality by regularly sending samples of our medications to an independent lab for verification of potency and to determine if there is contamination, all to bring you quality in every prescription.
 
Compounding has become much more advanced in formulating a wider variety of medications which can be transported using transdermals, through the skin, to the treatment area. The advancement of these medications alleviate systemic side effects associated with some chemicals i.e. gastric disturbances, as well as allow the active ingredients to be given in smaller dosages due to the proximity of the medicine to the site of treatment.

A number of studies have shown that pluronic lecithin organogels (PLOs) have the unique capacity to deliver drugs across the epidermal barrier and deliver particular medications to specific tissue. PLO gel looks and feels like a cream but is actually a gel. Combining the aqueous phase (pluronic gel) with the lecithin oil base creates an emulsion that holds together due to the surfactant qualities of the pluronic gel and the viscosity of that gel at room temperature. The PLO gel base disrupts the lipid layers of the stratum corneum (the outermost layer of the skin) without damaging the skin. The PLO gel base acts as a delivery system that allows transfer of the active ingredient across the stratum corneum into the dermal-epidermal blood flow. This process allows the medication to go right to the site of the pain.

Many types of products can be formulated into transdermal bases. Our pharmacy works with Anti-inflammatories and muscle relaxants (Baclofen and Cyclobenzaprine), anesthetics (Lidocaine), receptor antagonists (Ketamine) and neuropathic agents (Amitriptyline, Gabapentin, Acyclovir, and Clonidine).




We produce only the highest quality topical pain medications for:
 

arthritis
 
fibromyalgia
 
nerve damage
 
joint pain
 
sports injury
 
muscle strains
 
gout
 
shingles
 

Another major advantage of transdermal delivery is the ability to meet an individual patient’s needs in customizing a formula just for the patient. Because so many medications can be used to treat pain, the compounding pharmacist can work with the doctor and the patient to include those ingredients that are necessary to relieve the patient’s pain or discomfort.
There are many advantages to prescribing transdermal medication:
 

Less Overall Side Effects
 
No GI Discomfort or Distress
 
No Significant Systemic Side Effects
 
Localized Pain Relief
 
Lower Dosages
 
Non-Addictive
 
Increased Patient Compliance
 
Note: Compounded ingredients have been tested and approved by the FDA for their intended use.